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Antigenic Specificity | TNF-alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNF-alpha Polyclonal Antibody detects endogenous levels of TNF-alpha protein. TNF encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human TNF-alpha at AA range: 110-190 |
Other Names | [Rabbit TNF-alpha; TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a] |
Gene, Accession # | [TNF-alpha], Gene ID: 7124, NCBI: NP_000585.2, UniProt: P01375 |
Catalog # | MBS9700720 |
Price | $250, $250 |
Order / More Info | TNF-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |