PKLR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKLR
Clone[AT1E3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionPKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young.
ImmunogenImmunogen: Recombinant human PKLR (47-574aa) purified from E. coli
Other Names[Pyruvate kinase isozymes R/L; PK1; PKL; PKR; PKRL; RPK], [PKLR; PKLR; PK1; PKL; PKR; RPK; PKRL; PK1; PKL]
Gene, Accession #[PKLR], Gene ID: 5313, NCBI: NP_000289, UniProt: P30613
Catalog #MBS200204
Price$240, $315
Order / More InfoPKLR Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMeza NW., et al. (2009). Mol Ther. 17 (12):2000-9.; Roy MF., et al. (2007). J Exp Med. 204 (12):2949-61.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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