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Antigenic Specificity | PKLR |
Clone | [AT1E3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young. |
Immunogen | Immunogen: Recombinant human PKLR (47-574aa) purified from E. coli |
Other Names | [Pyruvate kinase isozymes R/L; PK1; PKL; PKR; PKRL; RPK], [PKLR; PKLR; PK1; PKL; PKR; RPK; PKRL; PK1; PKL] |
Gene, Accession # | [PKLR], Gene ID: 5313, NCBI: NP_000289, UniProt: P30613 |
Catalog # | MBS200204 |
Price | $240, $315 |
Order / More Info | PKLR Antibody from MYBIOSOURCE INC. |
Product Specific References | Meza NW., et al. (2009). Mol Ther. 17 (12):2000-9.; Roy MF., et al. (2007). J Exp Med. 204 (12):2949-61. |