DOCK2 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDOCK2 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis DOCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1812-1846 amino acids from the C-terminal region of human DOCK2. Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Immunogenn/a
Other Names[Dedicator of cytokinesis protein 2; DOCK2; KIAA0209]
Gene, Accession #[DOCK2], Gene ID: 1794, NCBI: NP_004937.1, UniProt: Q92608
Catalog #MBS9208979
Price$165, $370
Order / More InfoDOCK2 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesNagase T.,et al.DNA Res. 3:321-329(1996). Nishihara H.,et al.Biochim. Biophys. Acta 1452:179-187(1999). Nishihara H.,et al.Blood 100:3968-3974(2002). Nishihara H.,et al.Biochem. Biophys. Res. Commun. 296:716-720(2002). Cote J.-F.,et al.J. Cell Sci. 115:4901-4913(2002).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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