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Antigenic Specificity | DOCK2 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DOCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1812-1846 amino acids from the C-terminal region of human DOCK2. Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
Immunogen | n/a |
Other Names | [Dedicator of cytokinesis protein 2; DOCK2; KIAA0209] |
Gene, Accession # | [DOCK2], Gene ID: 1794, NCBI: NP_004937.1, UniProt: Q92608 |
Catalog # | MBS9208979 |
Price | $165, $370 |
Order / More Info | DOCK2 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Nagase T.,et al.DNA Res. 3:321-329(1996). Nishihara H.,et al.Biochim. Biophys. Acta 1452:179-187(1999). Nishihara H.,et al.Blood 100:3968-3974(2002). Nishihara H.,et al.Biochem. Biophys. Res. Commun. 296:716-720(2002). Cote J.-F.,et al.J. Cell Sci. 115:4901-4913(2002). |