PEA-15 (Phospho-Ser104) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PEA-15 (Phospho-Ser104) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of PEA-15 only when phosphorylated at serine 104. Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.Estelles A., J. Biol. Chem. 271:14800-14806(1996).Condorelli G., EMBO J. 17:3858-3866(1998).Wolford J.K., Gene 241:143-148(2000). |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 104(I-P-S(p)-A-K) derived from Human PEA-15. |
| Other Names | [PE15; PEA15; PED] |
| Gene, Accession # | [PEA-15], Gene ID: 8682, NCBI: NP_001284505.1, UniProt: Q15121 |
| Catalog # | MBS9407381 |
| Price | $200, $255 |
| Order / More Info | PEA-15 (Phospho-Ser104) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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