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Antigenic Specificity | CAMK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization and neurite outgrowth. Recognizes the substrate consensus sequence [MVLIF]-x-R-x2-[ST]-x3-[MVLIF]. Regulates axonal extension and growth cone motility in hippocampal and cerebellar nerve cells. Upon NMDA receptor-mediated Ca2+ elevation, promotes dendritic growth in hippocampal neurons and is essential in synapses for full long-term potentiation (LTP) and ERK2-dependent translational activation. Downstream of NMDA receptors, promotes the formation of spines and synapses in hippoc |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 271-370 of human CAMK1 (NP 003647.1). |
Other Names | [CAMKI] |
Gene, Accession # | [CAMK1], Gene ID: 8536, NCBI: NP_003647.1, UniProt: Q14012 |
Catalog # | MBS8546517 |
Price | $280 |
Order / More Info | CAMK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |