Dermatopontin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDermatopontin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Dermatopontin antibody detects endogenous levels of Dermatopontin. Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).Subunit Structure: Interacts with TGFB1, DCN and collagen.Post-translational Modifications: Sulfated on tyrosine residue(s).Similarity: Belongs to the dermatopontin family.
ImmunogenImmunogen: A synthesized peptide derived from human Dermatopontin. Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.
Other Names[DERM_HUMAN; Dermatopontin; Dpt; TRAMP; Tyrosine rich acidic matrix protein; Tyrosine-rich acidic matrix protein]
Gene, Accession #[DPT], Gene ID: 1805, NCBI: NP_001928.2, UniProt: Q07507
Catalog #MBS9603424
Price$240, $280
Order / More InfoDermatopontin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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