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Antigenic Specificity | Dermatopontin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dermatopontin antibody detects endogenous levels of Dermatopontin. Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).Subunit Structure: Interacts with TGFB1, DCN and collagen.Post-translational Modifications: Sulfated on tyrosine residue(s).Similarity: Belongs to the dermatopontin family. |
Immunogen | Immunogen: A synthesized peptide derived from human Dermatopontin. Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. |
Other Names | [DERM_HUMAN; Dermatopontin; Dpt; TRAMP; Tyrosine rich acidic matrix protein; Tyrosine-rich acidic matrix protein] |
Gene, Accession # | [DPT], Gene ID: 1805, NCBI: NP_001928.2, UniProt: Q07507 |
Catalog # | MBS9603424 |
Price | $240, $280 |
Order / More Info | Dermatopontin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |