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Antigenic Specificity | GRB2 |
Clone | [5G3-E7-F11] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 4.2mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human GRB2. Sensitivity: This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins. Sequence Similarities: Belongs to the GRB2/sem-5/DRK family. Contains 1 SH2 domain. Contains 2 SH3 domains. |
Other Names | [Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3; Growth factor receptor bound protein 2; Growth factor receptor bound protein 3; Growth factor receptor-bound protein 2; HT027; MST084; MSTP084; NCKAP2; OTTHUMP00000166096; OTTHUMP00000166097; OTTHUMP00000166098; Protein ASH; SEM5; SH2/SH3 adapter GRB2], [ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2] |
Gene, Accession # | [GRB2], Gene ID: 2885, NCBI: NP_002077.1, UniProt: P62993 |
Catalog # | MBS475234 |
Price | $335 |
Order / More Info | GRB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |