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Antigenic Specificity | NKX61 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NKX61 antibody detects endogenous levels of total NKX61. Function: Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).Similarity: The C-terminal domain contributes to sequence-specific DNA-binding. |
Immunogen | Immunogen: A synthesized peptide derived from human NKX61 Subcellular Location: Nucleus. Tissue Specificity: Pancreatic beta cells. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Xenopus (100%) |
Other Names | [Homeobox protein NK-6 homolog A; Homeobox protein Nkx-6.1; NK homeo box, family 6, member A; NK homeobox (Drosophila), family 6, A; NK homeobox, family 6, A; NK6 homeobox 1; NK6 transcription factor homolog A; NK6 transcription factor related, locus 1; NK6 transcription factor related, locus 1 (Drosophila); NKX6-1; NKX6.1; NKX61; NKX61_HUMAN; NKX6A] |
Gene, Accession # | [NKX61], Gene ID: 4825, NCBI: NP_006159.2, UniProt: P78426 |
Catalog # | MBS9609906 |
Price | $240, $280 |
Order / More Info | NKX61 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |