ARA9/AIP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityARA9/AIP
Clone[10G8]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, monkey
IsotypeIgG2b
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for ARA9/AIP detection. Tested with Tested with WB, IHC-P, IHC-F, ICC/IF in Human; Mouse; Rat; Monkey.Background: AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutati
ImmunogenImmunogen: E Coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.
Other Names[AH receptor-interacting protein; AIP; Aryl-hydrocarbon receptor-interacting protein; HBV X-associated protein 2; XAP-2; Immunophilin homolog ARA9; AIP; XAP2; Aryl hydrocarbon receptor interacting protein]
Gene, Accession #[ARA9], Gene ID: 9049, NCBI: NP_001289888.1, UniProt: O00170
Catalog #MBS1752231
Price$315
Order / More InfoARA9/AIP Antibody from MYBIOSOURCE INC.
Product Specific References1. Carver LA, Bradfield CA (April 1997). Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J. Biol. Chem. 272 (17): 11452-6. 2. Kuzhandaivelu, N., Cong, Y.-S., Inouye, C., Yang, W.-M., Seto, E. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res. 24: 4741-4750, 1996. 3. Occhi G, Trivellin G, Ceccato F, et al. (2010). Prevalence of AIP mutations in a large series of sporadic Italian acromegalic patients and evaluation of CDKN1B status in acromegalic patients with multiple endocrine neoplasia.. Eur. J. Endocrinol. 163 (3): 369-376.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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