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Antigenic Specificity | Estrogen Receptor alpha (ER-alpha) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~67 kDa of human estrogen receptor. This antibody reacts with human. The other species are not tested. ER (estrogen receptor) belongs to a member of the steroid receptor superfamily, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. This protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. ER regulates trans |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [ER-alpha], Gene ID: 2099 |
Catalog # | MBS460118 |
Price | $285 |
Order / More Info | Estrogen Receptor alpha (ER-alpha) Antibody from MYBIOSOURCE INC. |
Product Specific References | Campbell, R.A., Bhat-Nakshatri, P., Patel, N.M., Constantinidou, D., Ali, S. and Nakshatri, H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J. Biol. Chem. 276 (13), 9817-9824 (2001). |