CD1b (T-Cell Surface Glycoprotein) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD1b (T-Cell Surface Glycoprotein) |
| Clone | [100-1A5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expre |
| Immunogen | Immunogen: Stimulated human leukocytes |
| Other Names | [A1 domain; CD1B; Cortical thymocyte antigen CD1B; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1b; T6/Leu6], [CD1B; CD1B; R1; CD1; CD1A] |
| Gene, Accession # | [CD1B], Gene ID: 910, NCBI: NP_001755.1, UniProt: P29016 |
| Catalog # | MBS439494 |
| Price | $190, $340, $340 |
| Order / More Info | CD1b (T-Cell Surface Glycoprotein) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Knapp W. et al. (eds) Leukocyte Typing IV, p251-263, Oxford University Press, Oxford, 1989. Battistini L, et al. CD1b is expressed in multiple sclerosis lesions. J Neuroimmunol 1996, 67(2):145-151. Khalili-Shirazi A, et al. The distribution of CD1 molecules in inflammatory neuropathy. J Neurol Sci 1998,158(2):154-163. Maher JK and Kronenberg M. The role of CD1 molecules in immune responses to infection. Curr Opin Immunol 1997, 9(4):456-461Blumberg RS et al. Structure and function of the CD1 family of MHC-like cell surface proteins. Immunol Rev 1995, 147:5-29. Salamone MC et al. Analysis of CD1 molecules on haematological malignancies of myeloid and lymphoid origin. II. Intracellular detection of CD1 antigens. Dis Markers 1990, 8(5):275-281 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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