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Antigenic Specificity | ACTN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ACTN2 antibody detects endogenous levels of total ACTN2. Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.Subunit Structure: Homodimer; antiparallel. Also forms heterodimers with ACTN3. Interacts with ADAM12, MYOZ1, MYOZ2 and MYOZ3. Interacts via its C-terminal region with the LDB3 PDZ domain. Interacts with XIRP2. Interacts with DST isoform 1 (via N-terminus). Interacts with PARVB. Interacts with SYNPO2.Post-translational Modifications: Ubiquitinated by FBXL22, leading to proteasomal degradation.Similarity: Belongs to the alpha-actinin family. |
Immunogen | Immunogen: A synthesized peptide derived from human ACTN2 Subcellular Location: Cytoplasm > Myofibril > Sarcomere > Z Line. Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle. Tissue Specificity: Expressed in both skeletal and cardiac muscle. |
Other Names | [Actin binding protein; Actinin alpha 2; ACTN 2; ACTN2; ACTN2_HUMAN; Alpha actinin 2; Alpha actinin skeletal muscle; Alpha actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; CMD1AA; F actin cross linking protein; F-actin cross-linking protein] |
Gene, Accession # | [ACTN2], Gene ID: 88, NCBI: NP_001094.1, UniProt: P35609 |
Catalog # | MBS9608365 |
Price | $240, $280 |
Order / More Info | ACTN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |