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Antigenic Specificity | PRPS1 |
Clone | [AT1E11] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5). |
Immunogen | Immunogen: PRPS1 antibody was raised in Mouse using recombinant human PrPS1 (1-318aa) purified from E Coli as the immunogen |
Other Names | [Mouse PRPS1; PRPS1; PRPS1; ARTS; CMTX5; PPRibP; PRSI; DFN2; DFNX1; Ribose-phosphate pyrophosphokinase 1 EC 2761; KIAA0967; Phosphoribosyl pyrophosphate synthetase I; PRS I; PRS-I; Ribose phosphate pyrophosphokinase I] |
Gene, Accession # | [PRPS1], Gene ID: 5631, NCBI: AKI70238.1 |
Catalog # | MBS5310668 |
Price | $270 |
Order / More Info | PRPS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |