DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker) |
| Clone | [SPM580] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%. |
| Immunogen | Immunogen: Recombinant human DOG-1 protein |
| Other Names | [Anoctamin 1, Calcium Activated Chloride Channel, Discovered On Gastrointestinal Stromal Tumors Protein 1,TAOS2, ORAOV2, TMEM16A], [ANO1; ANO1; DOG1; TAOS2; ORAOV2; TMEM16A; DOG1; ORAOV2; TAOS2; TMEM16A] |
| Gene, Accession # | [TMEM16A], Gene ID: 55107, NCBI: NP_060513.5, UniProt: Q5XXA6 |
| Catalog # | MBS438426 |
| Price | $190, $340, $340 |
| Order / More Info | DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Espinosa I, et. al. Am J Surg Pathol 2008;32:210-218 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.