CABYR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCABYR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CABYR antibody detects endogenous levels of total CABYR. Function: May function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.Subunit Structure: Interacts with FSCB (By similarity). Isoform 3 self-associates. Isoform 3 and isoform 5 interact with GSK3B. Isoform 1 does not interact with GSK3B.Post-translational Modifications: Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation aff
ImmunogenImmunogen: A synthesized peptide derived from human CABYR Subcellular Location: Cytoplasm > Cytoskeleton. Cell projection > Cilium > Flagellum. Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella and nucleus. cytoplasm. Cell Projection > Cilium > Flagellum. According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic. Tissue Specificity: Expressed in elongating spermatids and spermato
Other Names[CABYR; CABYR_HUMAN; Calcium binding tyrosine-(Y)-phosphorylation regulated; Calcium-binding protein 86; Calcium-binding tyrosine phosphorylation-regulated protein; Cancer/testis antigen 88; CBP86; CT88; Fibrousheathin II; Fibrousheathin-2; FSP-2; FSP2; Testis-specific calcium-binding protein CBP86]
Gene, Accession #[CABYR], Gene ID: 26256, NCBI: NP_036321.2, UniProt: O75952
Catalog #MBS9609627
Price$240, $280
Order / More InfoCABYR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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