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Antigenic Specificity | CABYR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CABYR antibody detects endogenous levels of total CABYR. Function: May function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.Subunit Structure: Interacts with FSCB (By similarity). Isoform 3 self-associates. Isoform 3 and isoform 5 interact with GSK3B. Isoform 1 does not interact with GSK3B.Post-translational Modifications: Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation aff |
Immunogen | Immunogen: A synthesized peptide derived from human CABYR Subcellular Location: Cytoplasm > Cytoskeleton. Cell projection > Cilium > Flagellum. Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella and nucleus. cytoplasm. Cell Projection > Cilium > Flagellum. According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic. Tissue Specificity: Expressed in elongating spermatids and spermato |
Other Names | [CABYR; CABYR_HUMAN; Calcium binding tyrosine-(Y)-phosphorylation regulated; Calcium-binding protein 86; Calcium-binding tyrosine phosphorylation-regulated protein; Cancer/testis antigen 88; CBP86; CT88; Fibrousheathin II; Fibrousheathin-2; FSP-2; FSP2; Testis-specific calcium-binding protein CBP86] |
Gene, Accession # | [CABYR], Gene ID: 26256, NCBI: NP_036321.2, UniProt: O75952 |
Catalog # | MBS9609627 |
Price | $240, $280 |
Order / More Info | CABYR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |