Troponin I Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Troponin I antibody, protein, ELISA kits.
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| Antigenic Specificity | Troponin I |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human Troponin I. Troponin, working in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in the intracellular Ca2+ concentration. Troponin consists of three subunits: the Ca2+-binding subunit troponin C (TnC), the tropomyosin-binding subunit troponin T (TnT), and the inhibitory subunit troponin I (TnI) (1). In response to beta-adrenergic stimulation of the heart, Ser23 and Ser24 of TnI (cardiac) are phosphorylated by PKA and PKC. This phosphorylation stimulates a conformational change of the regulatory domain of TnC, reduces the association between TnI and TnC, and decreases myofilament Ca2+ sensitivity by reducing the Ca2+ binding affinity of TnC (1-3). |
| Immunogen | Immunogen: A synthetic -peptide of human Troponin I |
| Other Names | [TNNI3; TNNT1; ANM; FLJ98147; MGC104241; STNT; TNT; TNTS], [TNNI3; TNNI3; CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF; TNNC1] |
| Gene, Accession # | Gene ID: 7137, NCBI: NP_000354.4, UniProt: P19429 |
| Catalog # | MBS125497 |
| Price | $200, $275, $430 |
| Order / More Info | Troponin I Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Ward, D.G. et al. (2002) J. Biol. Chem. 277, 41795-41801. 2. Noland, T.A. et al. (1995) J. Biol. Chem. 270, 25445-25454. 3. Gaponenko, V. et al. (1999) J. Biol. Chem. 274, 16681-16684. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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