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Antigenic Specificity | RABEX5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members. RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide near the center terminus of human RABEX5. |
Other Names | [Rab5 GDP, GTP exchange factor, RABGEF1] |
Gene, Accession # | [RABEX5], Gene ID: 27342, NCBI: NP_055319 |
Catalog # | MBS9409927 |
Price | $320 |
Order / More Info | RABEX5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |