Apoptosis-inducing factor 1 (AIF) (1B7) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Apoptosis-inducing factor 1 (AIF) (1B7) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, monkey, Chinese hamster, dog |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: AIF (1B7) Mouse mAb detects endogenous levels of total AIF protein. A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases 2, 3, and 9 and AIF (apoptosis-inducing factor). AIF was shown to cause DNA fragmentation and chromatin condensation, and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression was shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity. |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to residues within the carboxy terminus of AIF. |
| Other Names | [apoptosis-inducing factor 1, mitochondrial isoform AIF; Apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor 1, mitochondrial; apoptosis inducing factor mitochondria associated 1; Programmed cell death protein 8], [AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8] |
| Gene, Accession # | [AIF], Gene ID: 9131, NCBI: NP_004199.1, UniProt: O95831 |
| Catalog # | MBS435001 |
| Price | $350, $565 |
| Order / More Info | Apoptosis-inducing factor 1 (AIF) (1B7) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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