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Antigenic Specificity | huPGP9.5 (176-191) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | primate, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL, 0.15 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Endomorphins are recently discovered endogenous opioid peptides composed of four amino acids: Endomorphin-1 (EM-1) is Tyr-Pro-Trp-Phe-NH2, and Endomorphin-2 (EM-2) is Tyr-Pro-Phe-Phe-NH2. These peptides have a very high affinity and specificity for mu-opioid receptors as it has been reported in many pharmacological studies. EM-1 is distributed in many brain regions, whereas EM-2 is prevalent in brainstem and spinal cord. EM-1 and EM-2 exert their antinociceptive activity by interacting with mu-opioid receptors. EM-1 anf EM-2 bind with mu-opioid receptor with high affinity and selectivity in comparison with binding to opioid delta and kappa receptors. EM-1 and EM-2 tetrapeptides activate G-proteins and inhibit adenylyl cyclase activity when |
Immunogen | Immunogen: YPFF conjugated to BSA |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS555596 |
Price | $235, $445 |
Order / More Info | huPGP9.5 (176-191) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |