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Antigenic Specificity | IFNAR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFNAR2 antibody detects endogenous levels of total IFNAR2. Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.Function: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their |
Immunogen | Immunogen: A synthesized peptide derived from human IFNAR2 Subcellular Location: Secreted and Membrane. Tissue Specificity: Isoform 3 is detected in the urine (at protein level) (PubMed:8181059, PubMed:7759950). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. Predicted Cross Reactivity: Dog Similarity: Dog (83%) |
Other Names | [Human interferon alpha/beta receptor; IFN alpha REC; IFN R; IFN-a/betaR2; IFN-a/betaRbeta; IFN-alpha binding protein; IFN-alpha/beta receptor 2; IFN-R-2; IFNABR; IFNAR2; IFNARB; IFNR; INAR2_HUMAN; Interferon (alpha beta and omega) receptor 2; Interferon alpha binding protein; Interferon alpha/beta receptor 2; Interferon alpha/beta receptor beta chain; Type I interferon receptor 2; Type I interferon receptor] |
Gene, Accession # | [IFNAR2], Gene ID: 3455, NCBI: NP_000865.2, UniProt: P48551 |
Catalog # | MBS9607261 |
Price | $240, $280 |
Order / More Info | IFNAR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |