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Antigenic Specificity | SGTA |
Clone | [AT19E8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protein is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. |
Immunogen | Immunogen: Recombinant human SGTA (1-313aa) purified from E. coli |
Other Names | [Small glutamine-rich tetratricopeptide repeat-containing protein alpha; alphaSGT; hSGT; SGT; Small glutamine-rich tetratricopeptide repeat-containing protein alpha Small glutamine rich tetratricopeptide repeat TPR containing alpha; uBP; Vpu binding protein.], [SGTA; SGTA; SGT; hSGT; alphaSGT; SGT; SGT1; UBP] |
Gene, Accession # | [SGTA], Gene ID: 6449, NCBI: NP_003012, UniProt: O43765 |
Catalog # | MBS200407 |
Price | $240, $315 |
Order / More Info | SGTA Antibody from MYBIOSOURCE INC. |
Product Specific References | Andreyeva A., et al. (2010) PLoS One. 5: e12018.; Cziepluch C., et al. (1998) J Virol. 72 (5): 4149-56.; |