Edit |   |
---|---|
Antigenic Specificity | CD3 Epsilon |
Clone | [RBT-CD3e] |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The CD3 antigen is a protein complex composed of three distinct chains (CD3gamma, CD3delta and CD3epsilon) that associate with T-cell receptors and the zeta-chain to generate an activation signal in T-lymphocytes. The TCR, zeta-chain and CD3 molecules together comprise the TCR complex. The CD3gamma, CD3delta and CD3epsilon chains are highly-related cell surface proteins of the immunoglobulin superfamily containing a single extracellular immunoglobulin domain. The intracellular tails of the CD3 molecules contain a single conserved motif known as an immunoreceptor tyrosine-based activation motif (or ITAM for short), which is essential for the signaling capacity of the TCR. Phosphorylation of the ITAM on CD3 renders the CD3 chain capable of bi |
Immunogen | n/a |
Other Names | [CD3 Epsilon RMab], [cd3g; cd3] |
Gene, Accession # | [CD3 Epsilon], UniProt: P79951 |
Catalog # | MBS370024 |
Price | $130, $185, $255 |
Order / More Info | CD3 Epsilon Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |