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Antigenic Specificity | ATG12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATG12 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG12, another member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as |
Immunogen | Immunogen: ATG12 antibody was raised against a 15 amino acid synthetic peptide from near the center of human ATG12. Buffer: ATG12 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ATG12; APG12; FBR93; APG12L; HAPG12; APG12; Ubiquitin-like protein ATG12; Autophagy-related protein 12; APG12-like; ATG12 autophagy related 12 homolog (S. cerevisiae)], [ATG12; ATG12; APG12; FBR93; APG12L; HAPG12; APG12; APG12L; APG12-like] |
Gene, Accession # | [ATG12], Gene ID: 9140, NCBI: EAW48955, UniProt: O94817 |
Catalog # | MBS151081 |
Price | $375 |
Order / More Info | ATG12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |