Hexokinase 1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Hexokinase 1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Hexokinase 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist. There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1). Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2). Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3). It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4). |
| Immunogen | Immunogen: Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: Rat Bladder Tissue Lysate |
| Other Names | [Hexokinase 1; HK; HXK], [HK1; HK1; HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc; HK I] |
| Gene, Accession # | [HK1], Gene ID: 3098, NCBI: NP_000179, UniProt: P19367 |
| Catalog # | MBS154388 |
| Price | $375 |
| Order / More Info | Hexokinase 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chen T, Ning D, Sun H, et al. Sequence Analysis and Molecular Characterization of Clonorchis sinensis Hexokinase 1, an Unusual Trimeric 50-kDa Glucose-6-Phosphate-Sensitive Allosteric Enzyme. PLoS One 2014; 9:e107940. Halestrap AP, Pereira GC, and Pasdois P. The role of Hexokinase 1 in cardioprotection-mechanism and potential for translation. Br. J. Pharmacol. 2014; epub. Roberts DJ and Miyamoto S. Hexokinase 1 II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy. Cell Death Differ. 2014; epub. Wang L, Xiong H, Wu F, et al. Hexokinase 1 2-Mediated Warburg Effect Is Required for PTEN- and p53-Deficiency-Driven Prostate Cancer Growth. Cell Rep. 2014; 8:1461-74. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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