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Antigenic Specificity | ATF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATF1 Antibody detects endogenous levels of ATF1. Description: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.Post Translational Modifications: Phosphorylated at Ser-198 by HIPK2 in response to genotoxic stress. This phosphorylation promotes transcription repression of FTH1 and other antioxidant detoxification genes. The CDK3-mediated phosphorylation at Ser-63 promotes its transactivation and tran |
Immunogen | Immunogen: A synthesized peptide derived from human ATF1. |
Other Names | [Activating transcription factor 1; ATF 1; atf1; ATF1 EWS fusion gene; ATF1 FUS fusion gene; ATF1_HUMAN; cAMP dependent transcription factor 1; cAMP-dependent transcription factor ATF-1; Cyclic AMP dependent transcription factor ATF 1; Cyclic AMP dependent transcription factor ATF1; Cyclic AMP-dependent transcription factor ATF-1; EWS AFT1; FUS ATF 1; FUS/ATF 1; Protein TREB36; RNA binding protein activating transcription factor 1 fusion protein; TREB 36; TREB36; TREB36 protein] |
Gene, Accession # | [ATF1], Gene ID: 466, NCBI: NP_005162.1, UniProt: P18846 |
Catalog # | MBS9611040 |
Price | $225, $280, $340 |
Order / More Info | ATF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |