Alpha-Actin, smooth muscle Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Alpha-Actin, smooth muscle |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, other vertebrates |
| Isotype | n/a |
| Format | unconjugated |
| Size | 5 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody 1A4 detects alpha-actin of smooth muscle origin, thus it is suitable to distinguish smooth muscle cells from cells of sarcomeric origin. It may also be used for differentiation from fibroblast actin (F-actin). Movement of cell organelles, cells, and organisms depends on the interaction of the cytoskeletal proteins actin and myosin. In birds and mammals up to now six different isoforms of actin have been identified using amino acid sequence analysis and electrophoresis. They are more or less specific for different organs resp. cell types. Four isoforms are known to occur in muscle cells, while two other forms are found in most other cell types. Alpha-Actin, smooth muscle. |
| Immunogen | Immunogen: Synthetic N-terminal decapeptide of smooth muscle Alpha-Actin |
| Other Names | [actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein], [ACTA2; ACTA2; ACTSA; ACTSA; ACTVS] |
| Gene, Accession # | Gene ID: 59, NCBI: NP_001135417.1, UniProt: P62736 |
| Catalog # | MBS396748 |
| Price | $320 |
| Order / More Info | Alpha-Actin, smooth muscle Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Skalli O, Ropraz P., Trzeciak A., Benzonana G., Gillessen D. Gabbiani G. (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J. Cell Biol. 103; 2787-2796. 2. Skalli O., Schurch W., Seemayer T., Lagace R., Montandon D., Pittet B., et al. (1989) Myofibroblasts from diverse pathologic settings are heterogenous in their content of actin isoforms and intermediate filament proteins. Lab Invest. 60; 275-285. 3. Ronnov-Jessen L., Van Deurs B., Celis J.E., and Petersen O.W. (1990) Smooth muscle differentiation in cultured human breast gland stromal cells. Lab. Invest. 63; 532-543. 4. Hasegawa T., Hirose T., Kudo E., Abe J., and Hizawa K. (1990) Cytosteletal characteristics of myofibroblasts in benign and reactive fibroblastic lesions. Virch. Arch. (A) Pathol. Anat. 416; 375-382. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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