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Antigenic Specificity | RCC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RCC1 antibody detects endogenous levels of total RCC1. Function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved i |
Immunogen | Immunogen: A synthesized peptide derived from human RCC1 Subcellular Location: Nucleus. Cytoplasm. Becomes dispersed throughout the cytoplasm during mitosis. |
Other Names | [Cell cycle regulatory protein; CHC 1; CHC1; Chromosome condensation 1; Chromosome condensation protein 1; Guanine nucleotide releasing protein; HERC2; Ran GEF; RanGEF; RCC 1; RCC1; RCC1 I; RCC1_HUMAN; Regulator of chromosome condensation 1; Regulator of chromosome condensation; SHEP1; SNHG3 RCC1; SNHG3 RCC1 readthrough transcript] |
Gene, Accession # | [RCC1], Gene ID: 1104, NCBI: NP_001041659.1, UniProt: P18754 |
Catalog # | MBS9608676 |
Price | $240, $280 |
Order / More Info | RCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |