Edit |   |
---|---|
Antigenic Specificity | IL1b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL1 is a name that designates two pleiotropic cytokines, IL1 alpha (IL1F1) and IL1Beta (IL1F2), which are the products of distinct genes. IL1 alpha and IL1Beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1 alpha and IL1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL1 RI binds directly to IL1 alpha or IL1Beta and then associates with IL1 R accessory protein (IL1 R3/IL1 R AcP) to form a highaffinity receptor complex that is competent for signal transduction. IL1 RII has high affinity for IL1Bet |
Immunogen | Immunogen: IL1b antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human IL1B as the immunogen |
Other Names | [Affinity Purified Goat IL1b; IL1b; IL1b; ILb 1; Interlekin 1 beta; IL1b; ILb-1; IL-1b; IL1 beta; ILb-1; ILb 1] |
Gene, Accession # | [IL1b], Gene ID: 3553 |
Catalog # | MBS5312674 |
Price | $330 |
Order / More Info | IL1b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |