Calnexin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCalnexin
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionCalcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.
ImmunogenImmunogen: A synthesized peptide derived from human Calnexin. Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed: 12643545, PubMed: 17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed: 22314232).
Other Names[Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90; CANX], [CANX; CANX; CNX; P90; IP90]
Gene, Accession #[CANX], Gene ID: 821, NCBI: NP_001019820.1, UniProt: P27824
Catalog #MBS179957
Price$160, $340, $340
Order / More InfoCalnexin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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