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Antigenic Specificity | Calnexin |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. |
Immunogen | Immunogen: A synthesized peptide derived from human Calnexin. Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed: 12643545, PubMed: 17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed: 22314232). |
Other Names | [Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90; CANX], [CANX; CANX; CNX; P90; IP90] |
Gene, Accession # | [CANX], Gene ID: 821, NCBI: NP_001019820.1, UniProt: P27824 |
Catalog # | MBS179957 |
Price | $160, $340, $340 |
Order / More Info | Calnexin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |