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Antigenic Specificity | CRTC3 |
Clone | [5G9] |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain |
Immunogen | Immunogen: Purified recombinant fragment of human CRTC3 expressed in E. Coli. |
Other Names | [TORC3; FLJ21868; CRTC3] |
Gene, Accession # | [CRTC3], Gene ID: 64784, NCBI: NP_001036039.1, UniProt: Q6UUV7 |
Catalog # | MBS8538745 |
Price | $280 |
Order / More Info | CRTC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |