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Antigenic Specificity | Vang-like protein 1, VANGL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Vang-like protein 1 (VANGL1), also called Loop-tail protein 2 homolog (LPP2), is encoded by the VANGL1 gene, This gene contains 8 exons[1] and it maps to chromosome 1p13[2]. The VANGL1 protein is a 524-amino acid, 65KD protein, which has 4 transmembrane domains and a C-terminal ser/thr-x-val motif. Yagyu et al. (2002) found that downregulation of VANGL1 expression suppressed growth of a human hepatoma cell line.[1] Kalabis et al. (2006) found that VANGL1 overexpression enhanced this migration and wound closure in cultured cells.[3] |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of human VANGL1. |
Other Names | [Vang-like protein 1; VANGL1], [VANGL1; VANGL1; LPP2; STB2; STBM2; KITENIN; STB2; LPP2] |
Gene, Accession # | [VANGL1], Gene ID: 81839, NCBI: NP_620409.1, UniProt: Q8TAA9 |
Catalog # | MBS355202 |
Price | $275 |
Order / More Info | Vang-like protein 1, VANGL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Yagyu, R., Hamamoto, R., Furukawa, Y., Okabe, H., Yamamura, T., Nakamura, Y. Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma. Int. J. Oncol. 20: 1173-1178, 2002. 2. Katoh, M. Molecular cloning and characterization of Strabismus 2 (STB2). Int. J. Oncol. 20: 993-998, 2002. 3. Kalabis, J., Rosenberg, I., Podolsky, D. K. Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium. J. Biol. Chem. 281: 6434-6441, 2006 |