PON1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PON1 |
| Clone | [9D3] |
| Host Species | Mouse |
| Reactive Species | mouse, rat |
| Isotype | IgG2b |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA Capture (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for PON1 detection. Tested with WB, IHC-P, ELISA (Cap) in Mouse; Rat.Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and |
| Immunogen | Immunogen: E Coli-derived mouse PON1 recombinant protein (Position: A30-D274). |
| Other Names | [Serum paraoxonase/arylesterase 1; PON 1; Paraoxonase 1] |
| Gene, Accession # | [PON1], Gene ID: 18979, NCBI: NP_035264.2, UniProt: P52430 |
| Catalog # | MBS1751972 |
| Price | $315 |
| Order / More Info | PON1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Costa LG, Cole TB, Vitalone A, Furlong CE (2005). Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. CLINICA CHEMICA ACTA 352 (1-2): 37-47. 2. Khateeb J, Gantman A, Kreitenberg AJ, Aviram M, Fuhrman B (January 2010). Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway.Atherosclerosis 208 (1): 119-25. 3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (May 1996). The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics 33 (3): 498-507. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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