cIAP-1/HIAP-2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | cIAP-1/HIAP-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | dog, Gerbil, human, mouse, rat |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | cIAP1 (HIAP2, MIHB) is a member of the family of inhibitor of apoptosis proteins (IAP). IAPs suppress mitochondria-dependent and -independent apoptosis by binding to and inhibiting caspases through their BIR domains (reviewed in Liston et al, 2003; Wright and Duckett, 2005). Resistance towards apoptosis is a hallmark of cancer cells, and overexpression of IAPs can contribute to the development of cancer though inhibiting apoptosis. In addition to at least one BIR domain, some IAP members also have a RING-type finger motif at their carboxyl-terminal. The RING finger domain of several IAPs, including cIAP2, have E3 ubiquitin ligase activity and target the degradation of Smac/DIABLO through ubqiuitination. Smac/DIABLO is a death inducer and fu |
| Immunogen | Immunogen Information: Full-length recombinant protein of human cAIP1 was used as immunogen for this antibody |
| Other Names | [BIRC2; API1; IAP2; MIHB; RNF48; C-IAP1; IAP homolog B; IAP-2; Inhibitor of apoptosis protein 2; RING finger protein 48; TNFR2-TRAF-signaling complex protein 2; to cIAP-1/HIAP-2; cIAP-1/HIAP-2; cIAP-1/HIAP-2], [BIRC2; BIRC2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; API1; MIHB; RNF48; hIAP-2; hIAP2] |
| Gene, Accession # | [cIAP-1/HIAP-2], Gene ID: 329, NCBI: Q13490.2, UniProt: Q13490 |
| Catalog # | MBS668595 |
| Price | $270 |
| Order / More Info | cIAP-1/HIAP-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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