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Antigenic Specificity | PROS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PROS protein. PROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in PROS1 result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PROS protein at amino acid sequence of 20-100 |
Other Names | [Rabbit PROS; Vitamin K-dependent protein S] |
Gene, Accession # | [PROS], Gene ID: 5627, NCBI: P07225.1, UniProt: P07225 |
Catalog # | MBS9710551 |
Price | $130, $220, $325 |
Order / More Info | PROS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |