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Antigenic Specificity | Human Baculoviral IAP repeat-containing protein 7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of ap |
Immunogen | Immunogen: Recombinant human Baculoviral IAP repeat-containing protein 7 protein (1-265aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22964 / sc-33954 / sc-33955 / sc-22963 / sc-30161 |
Other Names | [Kidney inhibitor of apoptosis protein; KIAP; Livin; Melanoma inhibitor of apoptosis protein; ML-IAP; RING finger protein 50; Truncated livin; p30-Livin; tLivin; BIRC7; KIAP; LIVIN; MLIAP; RNF50], [BIRC7; BIRC7; KIAP; LIVIN; MLIAP; RNF50; ML-IAP; KIAP; LIVIN; MLIAP; RNF50; KIAP; ML-IAP; Truncated livin; p30-Livin; tLivin] |
Gene, Accession # | [BIRC7], Gene ID: 79444, NCBI: NP_071444.1, UniProt: Q96CA5 |
Catalog # | MBS1499897 |
Price | $120, $160 |
Order / More Info | Human Baculoviral IAP repeat-containing protein 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |