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Antigenic Specificity | HCLS1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against HCLS1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: HS1 which is hematopoietic lineage cell-specific protein 1, is a substrate of protein tyrosine kinases in lymphocytes, it binds to F-actin, and promotes Arp2/3 complex-mediated actin polymerization. However, the mechanism for the interaction between HS1 and F-actin has not yet been fully characterized. HS1 contains 3.5 tandem repeats, a coiled-coil region, and an SH3 domain at the C terminus. Unlike cortactin, which is closely related to HS1 and requires absolutely the repeat domain for F-actin binding, an HS1 mutant with deletion of the repeat domain maintains a significant F-actin bindi |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HCLS1 |
Other Names | [hematopoietic lineage cell-specific protein isoform 1; Hematopoietic lineage cell-specific protein; hematopoietic lineage cell-specific protein; hematopoietic cell-specific Lyn substrate 1; Hematopoietic cell-specific LYN substrate 1; LckBP1; p75] |
Gene, Accession # | [HCLS1], Gene ID: 3059, NCBI: NP_005326, UniProt: P14317 |
Catalog # | MBS3201049 |
Price | $270 |
Order / More Info | HCLS1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |