HCLS1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHCLS1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against HCLS1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: HS1 which is hematopoietic lineage cell-specific protein 1, is a substrate of protein tyrosine kinases in lymphocytes, it binds to F-actin, and promotes Arp2/3 complex-mediated actin polymerization. However, the mechanism for the interaction between HS1 and F-actin has not yet been fully characterized. HS1 contains 3.5 tandem repeats, a coiled-coil region, and an SH3 domain at the C terminus. Unlike cortactin, which is closely related to HS1 and requires absolutely the repeat domain for F-actin binding, an HS1 mutant with deletion of the repeat domain maintains a significant F-actin bindi
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HCLS1
Other Names[hematopoietic lineage cell-specific protein isoform 1; Hematopoietic lineage cell-specific protein; hematopoietic lineage cell-specific protein; hematopoietic cell-specific Lyn substrate 1; Hematopoietic cell-specific LYN substrate 1; LckBP1; p75]
Gene, Accession #[HCLS1], Gene ID: 3059, NCBI: NP_005326, UniProt: P14317
Catalog #MBS3201049
Price$270
Order / More InfoHCLS1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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