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Antigenic Specificity | MAP3K11/MLK3 |
Clone | [3D11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Formalin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human MAP3K11. Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14(p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role inmitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization duringthe cell cycle. |
Immunogen | Immunogen: MAP3K11 (NP 002410, 741 a.a. ~ 848 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human MAP3K11/MLK3; MAP3K11; Mixed lineage kinase 3; MLK3; Protein-tyrosine kinase PTK1; PTK1; SPRK; MLK-3; MEKK11] |
Gene, Accession # | [MAP3K11/MLK3], Gene ID: 4296, NCBI: NP_002410.1, UniProt: Q16584 |
Catalog # | MBS2400908 |
Price | $605 |
Order / More Info | MAP3K11/MLK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |