MAP3K11/MLK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP3K11/MLK3
Clone[3D11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, k
FormatProtein A purified
Size0.05 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
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DescriptionSpecificity: Human MAP3K11. Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14(p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role inmitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization duringthe cell cycle.
ImmunogenImmunogen: MAP3K11 (NP 002410, 741 a.a. ~ 848 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated
Other Names[Rabbit (IgG) to Human MAP3K11/MLK3; MAP3K11; Mixed lineage kinase 3; MLK3; Protein-tyrosine kinase PTK1; PTK1; SPRK; MLK-3; MEKK11]
Gene, Accession #[MAP3K11/MLK3], Gene ID: 4296, NCBI: NP_002410.1, UniProt: Q16584
Catalog #MBS2400908
Price$605
Order / More InfoMAP3K11/MLK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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