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Antigenic Specificity | IGF2BP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-579 of human IGF2BP3 (NP 006538.2). |
Other Names | [KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3] |
Gene, Accession # | [IGF2BP3], Gene ID: 10643, NCBI: NP_006538.2, UniProt: O00425 |
Catalog # | MBS8545386 |
Price | $280 |
Order / More Info | IGF2BP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |