PIAS3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIAS3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPIAS3 Antibody: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays mul
ImmunogenImmunogen: PIAS3 antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human PIAS3. Buffer: PIAS3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PIAS3; ZMIZ5; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3; protein inhibitor of activated STAT, 3], [PIAS3; PIAS3; ZMIZ5]
Gene, Accession #[PIAS3], Gene ID: 10401, NCBI: NP_006090, UniProt: Q9Y6X2
Catalog #MBS151112
Price$375
Order / More InfoPIAS3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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