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Antigenic Specificity | HLA-G (Center), 62-89 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.36 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HLA-G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the Central region of human HLA-G. HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. |
Immunogen | n/a |
Other Names | [HLA class I histocompatibility antigen; alpha chain G; HLA G antigen; MHC class I antigen G; HLA-G; HLA-60; HLAG] |
Gene, Accession # | [HLA-G], Gene ID: 3135, NCBI: NP_002118.1, UniProt: P17693 |
Catalog # | MBS9210369 |
Price | $165, $370 |
Order / More Info | HLA-G (Center), 62-89 Antibody from MYBIOSOURCE INC. |
Product Specific References | Walpole,N.G., et.al., J. Mol. Biol. 397 (2), 467-480 (2010) Tian,W., et.sl., Tissue Antigens 75 (3), 227-234 (2010) |