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Antigenic Specificity | c-fos |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes c-Fos protein. It cross-reacts to human, mouse, rat. The other species were not tested. The c-Fos proto-oncogene, an 55 kDa nuclear phosphor-protein, belongs to a family of transcription factors. It plays important roles in cell proliferation and differentiation. c-Fos is associated with the c-Jun protein, forming a stable c-Fos/c-Jun heterodimeric complex, this complex binds to the DNA promoter region which regulate transcription. Expression of the c-Fos gene is low in most normal adult tissues. However, high levels of expression have been detected in normal skin. |
Immunogen | n/a |
Other Names | [p55; c-FOS; AP-1], [FOS; FOS; p55; AP-1; C-FOS; G0S7] |
Gene, Accession # | [c-fos], Gene ID: 2353, NCBI: CAA24756.1, UniProt: P01100 |
Catalog # | MBS460212 |
Price | $285 |
Order / More Info | c-fos Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang, Z.Q., Ovitt, C., Grigoriadis, A.E., Mohle-Steinlein, U., Ruther, U. and Wagner, E.F. Bone and haematopoietic defects in mice lacking c-fos. Nature 360 (6406), 741-745 (1992). |