Edit |   |
---|---|
Antigenic Specificity | CDKN2A (N-term S8), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CDKN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDKN2A. This gene generates several transcript variants whichdiffer in their first exons. At least three alternatively splicedvariants encoding distinct proteins have been reported, two ofwhich encode structurally related isoforms known to function asinhibitors of CDK4 kinase. The remaining transcript includes analternate first exon located 20 Kb upstream of the remainder of thegene; this transcript contains an alternate open reading frame(ARF) that specifies a protein which is structurally unrelated tothe products of the other variants. This ARF product |
Immunogen | n/a |
Other Names | [Cyclin-dependent kinase inhibitor 2A; isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A; CDKN2A; CDKN2; MTS1] |
Gene, Accession # | [CDKN2A], Gene ID: 1029, NCBI: NP_000068.1, UniProt: P42771 |
Catalog # | MBS9209573 |
Price | $165, $370 |
Order / More Info | CDKN2A (N-term S8), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kovacs, E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(12):5429-5434(2010) Irvine, M., et al. Cell Cycle 9(4):829-839(2010) Zhang, H.J., et al. J. Cell. Biochem. 106(3):464-472(2009) Ivanchuk, S.M., et al. Cell Cycle 7(12):1836-1850(2008) Bandyopadhyay, K., et al. Biochemistry 46(49):14325-14334(2007) |