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Antigenic Specificity | Dynactin 1 (N-term) |
Clone | [3D5-C6-D5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding disti |
Immunogen | Immunogen: Purified recombinant Dynactin 1 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Dynactin 1 (N-terminus), and does not cross-react with related proteins. Sequence Similarities: Belongs to the dynactin 150 kDa subunit family.Contains 1 CAP-Gly domain. |
Other Names | [150 kDa dynein associated polypeptide; 150 kDa dynein-associated polypeptide; DAP 150; DAP-150; DAP150; DCTN 1; DCTN1; DCTN1_HUMAN; DP 150; DP-150; DP150; Dynactin 1 (p150 Glued (Drosophila) homolog); dynactin 1 (p150 glued homolog Drosophila); Dynactin 1; Dynactin subunit 1; Dynactin1; HMN7B; p135; p150 Glued (Drosophila) homolog; p150 glued; p150 glued homolog; p150 (GLUED) DROSOPHILA HOMOLOG OF; p150-glued; p150glued], [P135; DP-150; DAP-150] |
Gene, Accession # | [dctn1], Gene ID: 1639, NCBI: NP_001128512.1, UniProt: Q14203 |
Catalog # | MBS475110 |
Price | $335 |
Order / More Info | Dynactin 1 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |