NEDD4L Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNEDD4L
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ImmunogenImmunogen: Recombinant Protein
Other Names[E3 ubiquitin-protein ligase NEDD4-like isoform 2; E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2]
Gene, Accession #[NEDD4L], Gene ID: 23327, NCBI: NP_001138436.1, UniProt: Q96PU5
Catalog #MBS9127931
Price$200, $275, $430
Order / More InfoNEDD4L Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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