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Antigenic Specificity | NEDD4L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [E3 ubiquitin-protein ligase NEDD4-like isoform 2; E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2] |
Gene, Accession # | [NEDD4L], Gene ID: 23327, NCBI: NP_001138436.1, UniProt: Q96PU5 |
Catalog # | MBS9127931 |
Price | $200, $275, $430 |
Order / More Info | NEDD4L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |