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Antigenic Specificity | MRVI1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MRVI1. It was validated on Western BlotTarget Description: This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, a |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRVI1 |
Other Names | [protein MRVI1 isoform a; Protein MRVI1; protein MRVI1; murine retrovirus integration site 1 homolog; Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; JAW1-related protein MRVI1] |
Gene, Accession # | [MRVI1], Gene ID: 10335, NCBI: NP_001092049.2, UniProt: Q9Y6F6 |
Catalog # | MBS3209875 |
Price | $335 |
Order / More Info | MRVI1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |