DOK2 (C-term), 380-412 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DOK2 (C-term), 380-412 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DOK2 (C-term), 380-412 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.7 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DOK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-412 amino acids from the C-terminal region of human DOK2. Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction. Dok-2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases. By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop. Dok-2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung. Expression of bcr/abl induces additional tyrosine phosphorylation of the Dok1 and Dok2 proteins and their association with Ras-GAP. |
| Immunogen | n/a |
| Other Names | [Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2); DOK2] |
| Gene, Accession # | [DOK2], Gene ID: 9046, NCBI: NP_003965.2, UniProt: O60496 |
| Catalog # | MBS9208194 |
| Price | $165, $370 |
| Order / More Info | DOK2 (C-term), 380-412 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Salomon, A.R., et al., Proc. Natl. Acad. Sci. U.S.A. 100(2):443-448 (2003). Di Cristofano, A., et al., J. Biol. Chem. 273(9):4827-4830 (1998). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies