ADAM10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADAM10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionSpecificity: ADAM10 Antibody detects endogenous levels of total ADAM10. The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major alpha-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways.
ImmunogenImmunogen: A synthesized peptide derived from human ADAM10
Other Names[disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein; Disintegrin and metalloproteinase domain-containing protein 10; disintegrin and metalloproteinase domain-containing protein 10; ADAM metallopeptidase domain 10; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloprotease; CD_antigen: CD156c]
Gene, Accession #[ADAM10], Gene ID: 102, NCBI: NP_001101.1, UniProt: O14672
Catalog #MBS4750841
Price$335
Order / More InfoADAM10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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