CD8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD8
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC)
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DescriptionCD8 (cluster of differentiation 8, also known as T-cell antigen T8/LEU2) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein.1 The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides, but is frequently lost in other T-cell neoplasms.
ImmunogenImmunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse CD8.
Other Names[CD8], [CD8A; CD8]
Gene, Accession #[CD8], Gene ID: 403158, NCBI: NP_990566.1
Catalog #MBS355076
Price$275
Order / More InfoCD8 Antibody from MYBIOSOURCE INC.
Product Specific References1. Gao G, Jakobsen B (2000). Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol Today 21 (12): 630-6. 2. Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M (2003). Manual of Diagnostic Cytology (2 ed.). Greenwich Medical Media, Ltd. p. 73.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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