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Antigenic Specificity | EphA2 |
Clone | [3D7] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTk). Eph RTks and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer. |
Immunogen | Immunogen: Recombinant human EphA2 (559-976aa) purified from E. coli |
Other Names | [Ephrin receptor EphA2; epoxide hydrolase 1 microsomal (xenobiotic);], [EPHA2; EPHA2; ECK; CTPA; ARCC2; CTPP1; CTRCT6; ECK] |
Gene, Accession # | [EphA2], Gene ID: 1969, NCBI: NP_004422, UniProt: P29317 |
Catalog # | MBS200110 |
Price | $240, $315 |
Order / More Info | EphA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ireton RC, Chen J: (2005) Curr Cancer Drug Tarqets. 5 (3), 149-57; Nakamoto M, Berqemann AD: (2002) Microsc Res Tech. 59 (1), 58-67 |