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Antigenic Specificity | ZYX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The zyxin family of proteins includes LIMD1, ajuba, trip6 and zyxin, each of which contains three LIM domains at the carboxy-terminus. Zyxin family members associate with the actin cytoskeleton and are components of both the cell-cell junction adhesive complex and the integrin-mediated adhesive complex. They shuttle in and out of the nucleus where they may function in transcriptional activation (1).Zyxin is involved in the regulation of mechanical force-induced actin polymerization at focal adhesions (2), and in regulation of adhesion and migration, possibly through recruitment of Ena/VASP proteins to focal adhesions (3). Zyxin interacts with and may regulate the function of the tumor suppressor myopodin, which inhibits tumor growth and met |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Zyxin; ESP-2; HED-2], [ZYX; ZYX; ESP-2; HED-2] |
Gene, Accession # | [ZYX], Gene ID: 7791, NCBI: Q15942.1, UniProt: Q15942 |
Catalog # | MBS127996 |
Price | $200, $275, $430 |
Order / More Info | ZYX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |